NON-SURGICAL

Weight Loss Injections

Medically Supervised Weight Management & metabolic Transformation

The Art of GLP-1 Assisted Weight Loss & Long-Term Health Restoration

AT A GLANCE
Medications: Ozempic (Semaglutide) & Mounjaro (Tirzepatide)
Administration: Weekly Self-Injection
Supervision: Fully Medically Supervised Program
Results: Progressive over 3 – 12 Months

Weight Loss Injections - Medically Supervised Weight Management & metabolic Transformation

Medically Supervised Weight Management
& Lasting Metabolic Health

A common misconception about weight loss injections is that they are a shortcut or a substitute for healthy living. At Vivari, we understand that GLP-1 medications like Ozempic and Mounjaro are sophisticated, clinically proven metabolic tools — designed to work in harmony with your body’s own hormonal system to regulate appetite, improve insulin sensitivity, and support the kind of sustained, progressive weight loss that diet and exercise alone have been unable to deliver. Our Specialist Weight Loss Injection program in South Africa combines medically supervised GLP-1 therapy with personalised nutritional guidance and lifestyle coaching — delivering a comprehensive, clinically supported weight management journey that addresses both the physiological and behavioural dimensions of lasting transformation.

Exclusively at Vivari Aesthetics — South Africa’s premier destination for weight loss injections and
luxury medically supervised metabolic transformation.

Vivari Hotel Suite Room

01 | THE VIVARI EXPERIENCE

Recovery as an Art Form

Surgery is only the first step; restoration is the journey. At Vivari, we have transformed post-operative care into a curated experience. Your recovery is supported by a multidisciplinary team within our luxury clinical suites, ensuring that the days following your procedure are as serene as they are scientifically optimized.

24/7 Concierge Nursing

Expert medical care delivered within the privacy of your luxury suite.

Hyperbaric Oxygen Therapy

Accelerating cellular repair and significantly reducing post-operative swelling.

Intravenous Nutrition

Bespoke IV infusions designed to support the immune system and skin maturation.

Lymphatic Integration

Specialized post-surgical treatments at the Vivari Spa to refine your results.

02 | THE TREATMENT OVERVIEW

Weight Loss Injections

A masterful medically supervised approach to appetite regulation, metabolic health, and progressive weight loss.

The Vivari Specialist Weight Loss Injection program in South Africa represents a significant advance beyond traditional diet and exercise approaches to weight management. While lifestyle modification remains foundational to long-term health, GLP-1 receptor agonist medications address the underlying hormonal and metabolic mechanisms that make sustained weight loss genuinely difficult for many patients — providing powerful clinical support where willpower and discipline alone have proven insufficient.

By mimicking the body’s natural GLP-1 hormone — which regulates appetite, slows digestion, and improves insulin sensitivity — these medications create a consistent, physiologically supported reduction in hunger and caloric intake that enables progressive, sustainable weight loss over time. Because we combine GLP-1 therapy with comprehensive nutritional guidance and lifestyle coaching, the results of our weight loss injection program in Johannesburg are fundamentally more enduring than medication alone — delivering a transformed relationship with food, health, and metabolic wellbeing.

The Strategic Advantages

💎 Clinically Proven Efficacy: GLP-1 receptor agonist medications are among the most rigorously studied and clinically proven weight management tools available — with clinical trials demonstrating average weight loss of 10–20% of body weight over 6–12 months in appropriate candidates.

⚖️ Hormonal Root Cause Treatment: By addressing the underlying hormonal mechanisms that drive hunger, cravings, and metabolic dysfunction — rather than simply restricting calories through willpower — GLP-1 therapy provides a physiologically supported path to weight loss that is both more effective and more sustainable.

👁️ Comprehensive Medical Supervision: Every patient in our weight loss injection program benefits from continuous medical monitoring, personalised dosage management, nutritional guidance, and lifestyle coaching — ensuring safety, efficacy, and the most sustained possible results throughout the complete treatment period.

◎ Metabolic Health Benefits: Beyond weight loss, GLP-1 medications deliver significant secondary health benefits — improving insulin sensitivity, reducing blood pressure, lowering cardiovascular risk markers, and supporting the management of Type 2 diabetes and metabolic syndrome.

Medication Focus

Ozempic (Semaglutide): A once-weekly GLP-1 receptor agonist injection that mimics the body’s natural satiety hormone — reducing appetite, slowing gastric emptying, and improving insulin regulation to support progressive, sustained weight loss over time.

Mounjaro (Tirzepatide): A once-weekly dual GIP and GLP-1 receptor agonist — combining two complementary hormonal mechanisms to deliver more powerful appetite suppression, superior metabolic improvement, and greater average weight loss than single-receptor GLP-1 agents alone.

Medical Supervision Protocol: Every patient receives a comprehensive initial medical assessment, personalised medication selection and dosage titration, regular clinical reviews, nutritional guidance, and ongoing lifestyle coaching — ensuring the safest, most effective, and most sustained weight loss outcome.

Lifestyle Integration: Our weight loss injection program is designed to be combined with dietary modification and lifestyle change — using GLP-1 therapy as a powerful clinical tool to support and accelerate the healthy habits that make weight loss results genuinely lasting beyond the medication period.

03 | THE JOURNEY

Your Path to Vivari

From first consultation to lasting metabolic transformation, every step is designed with precision and care.

01 THE CONSULTATION

Your transformation begins with a comprehensive medical assessment evaluating your BMI, metabolic health, weight loss history, current medications, and any contraindications to GLP-1 therapy. We determine your suitability for Ozempic or Mounjaro, select the most appropriate medication for your individual profile, and design a bespoke treatment plan — combining medically supervised injection therapy with personalised nutritional guidance and lifestyle coaching.

02 THE PREPARATION

Following your consultation and medical clearance, your medication is prescribed and your injection training is conducted by our clinical team. You will be fully trained in safe, comfortable self-administration technique — ensuring complete confidence in managing your weekly injection independently at home throughout your treatment program.

03 THE PROGRAM

Your weekly GLP-1 injection is self-administered at home on a consistent day each week. Regular clinical reviews with your Vivari medical team monitor your weight loss progress, metabolic response, and overall health — with dosage titrated progressively upward according to your individual tolerance and treatment response.

04 THE RESULTS

Over three to twelve months of medically supervised GLP-1 therapy, progressive appetite regulation and metabolic improvement drive sustained, meaningful weight loss — with most patients achieving 10–20% reduction in body weight when combining medication with our comprehensive nutritional and lifestyle support program.

04 | CLINICAL CLARITY

For a comprehensive understanding of our clinical protocols, please explore the details below.

MEDICAL HISTORY AND EXAM Prepare to answer questions about your complete medical history, including previous weight loss attempts, current medications, history of diabetes, thyroid conditions, pancreatitis, cardiovascular disease, and any personal or family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2 — both of which are contraindications to GLP-1 therapy. Your physician will evaluate your BMI, metabolic health markers, blood pressure, and overall suitability for Ozempic or Mounjaro therapy before prescribing.

MEDICATION REVIEW A comprehensive review of all current medications is essential before initiating GLP-1 therapy. Certain medications — particularly insulin, sulphonylureas, and other diabetes medications — may require dosage adjustment when combined with GLP-1 receptor agonists. Your physician will review all prescriptions and supplements to ensure safe, appropriate co-administration throughout your weight loss injection program.

METABOLIC HEALTH ASSESSMENT We conduct a comprehensive baseline metabolic assessment — including blood glucose, HbA1c, lipid profile, liver function, and kidney function — to establish your metabolic health baseline, confirm your suitability for GLP-1 therapy, and provide the clinical foundation for monitoring your metabolic improvement throughout the program.

ESTABLISHING EXPECTATIONS We discuss how the Specialist Weight Loss Injection program achieves progressive weight loss through hormonal appetite regulation and metabolic improvement — setting realistic expectations around the gradual nature of results, the importance of dietary and lifestyle compliance, the titration schedule for your chosen medication, and the comprehensive monitoring program that supports your journey throughout.

MEDICATION SELECTION Based on your comprehensive medical assessment, your physician will recommend either Ozempic (Semaglutide) or Mounjaro (Tirzepatide) — selecting the most clinically appropriate medication for your individual metabolic profile, weight loss goals, and medical history. Mounjaro is generally recommended for patients seeking more powerful appetite suppression and greater average weight loss.

INJECTION TRAINING Before beginning your program, our clinical team provides comprehensive training in safe, comfortable self-injection technique. Both Ozempic and Mounjaro are administered via a simple pre-filled pen device — once weekly, subcutaneously into the abdomen, thigh, or upper arm — making self-administration straightforward and virtually painless for most patients.

DOSAGE TITRATION PROTOCOL Both medications are initiated at the lowest available dose and titrated progressively upward over several weeks — allowing your body to adjust gradually and minimising the risk of gastrointestinal side effects during the initial adaptation period. Your physician will guide your titration schedule based on your individual tolerance and treatment response.

DIETARY PREPARATION To maximise the effectiveness of GLP-1 therapy and minimise gastrointestinal side effects during the initial weeks, we provide specific dietary guidance — recommending smaller, more frequent meals, reduced fat and sugar intake, and increased protein consumption to support both appetite regulation and optimal metabolic response.

LIFESTYLE PREPARATION GLP-1 medications are most effective when combined with meaningful lifestyle modification. We initiate our nutritional guidance and lifestyle coaching program concurrently with medication — embedding the dietary habits and activity patterns that maximise weight loss results and ensure sustainability beyond the medication period.

ONGOING MONITORING Regular clinical reviews are scheduled throughout your program — monitoring weight loss progress, metabolic health markers, medication tolerance, and overall wellbeing. Dosage adjustments are made as needed to ensure the safest and most effective possible outcome throughout your complete weight loss injection program.

OZEMPIC (SEMAGLUTIDE) — ADMINISTRATION Ozempic is administered as a once-weekly subcutaneous injection using a simple pre-filled pen device. It is initiated at 0.25mg weekly for the first four weeks before titrating to 0.5mg — with further titration to 1mg or 2mg based on individual tolerance and clinical response. Inject on the same day each week, rotating injection sites between the abdomen, thigh, and upper arm.

MOUNJARO (TIRZEPATIDE) — ADMINISTRATION Mounjaro is administered as a once-weekly subcutaneous injection using a pre-filled pen device. It is initiated at 2.5mg weekly for the first four weeks before titrating progressively to 5mg, 7.5mg, 10mg, 12.5mg, or 15mg — based on individual tolerance and clinical response. The dual GIP and GLP-1 mechanism delivers superior appetite suppression and metabolic improvement at higher doses.

MANAGING SIDE EFFECTS The most common side effects of both medications are gastrointestinal — including nausea, vomiting, diarrhoea, and constipation — particularly during the initial weeks of treatment and following each dose increase. These typically subside as the body adjusts. Eating smaller portions, avoiding high-fat foods, and staying well hydrated significantly reduces the severity of initial side effects.

STORAGE & HANDLING Both Ozempic and Mounjaro must be stored in the refrigerator between 2°C and 8°C — never frozen. Once in use, Ozempic pens may be kept at room temperature below 30°C for up to 56 days. Mounjaro pens may be kept at room temperature below 30°C for up to 21 days. Always inspect the medication for clarity before use and never use if discoloured or cloudy.

INITIAL ASSESSMENT (WEEK 1) Comprehensive baseline medical assessment, metabolic blood panel, medication selection, prescription, and injection training. Your nutritional guidance and lifestyle coaching program is initiated simultaneously — establishing the dietary and lifestyle foundation that maximises your GLP-1 therapy results from day one.

EARLY PROGRESS REVIEW (WEEKS 4–8) First clinical review monitors early weight loss progress, medication tolerance, side effect management, and dietary compliance. Dosage is titrated upward if well tolerated. Nutritional guidance is reviewed and adjusted based on your early dietary response and lifestyle integration progress.

ACTIVE WEIGHT LOSS PHASE (MONTHS 3–6) Monthly clinical reviews monitor continued weight loss progress, metabolic health improvement, and dosage optimisation. Most patients achieve their most significant weight loss during this active phase — with appetite regulation, portion reduction, and dietary habits becoming progressively more established and sustainable.

LONG-TERM MAINTENANCE (6–12 MONTHS+) A structured long-term monitoring program assesses sustained weight loss, metabolic health markers, and medication continuation or cessation planning — ensuring the lifestyle and dietary transformation achieved during the active program is preserved and built upon for enduring, life-changing weight management success.

FREQUENTLY ASKED QUESTIONS

Weight loss injections at Vivari utilise GLP-1 receptor agonist medications — specifically Ozempic (Semaglutide) and Mounjaro (Tirzepatide) — to regulate appetite, slow gastric emptying, and improve insulin sensitivity. By mimicking the body’s natural satiety hormones, these medications create a consistent, physiologically supported reduction in hunger and caloric intake — enabling progressive, sustained weight loss when combined with our comprehensive nutritional and lifestyle support program.

Ideal candidates are adults with a BMI of 27 or above — particularly those with weight-related health conditions such as Type 2 diabetes, hypertension, or metabolic syndrome — who have not achieved sufficient weight loss through diet and exercise alone. Candidates must have no contraindications to GLP-1 therapy and be committed to combining medication with meaningful dietary and lifestyle modification throughout the program.

Ozempic (Semaglutide) is a single GLP-1 receptor agonist — mimicking one satiety hormone to regulate appetite and improve insulin sensitivity. Mounjaro (Tirzepatide) is a dual GIP and GLP-1 receptor agonist — targeting two complementary hormonal pathways simultaneously for more powerful appetite suppression, superior metabolic improvement, and greater average weight loss than Ozempic alone. Your physician will recommend the most appropriate medication based on your individual profile and goals.

Clinical trials demonstrate average weight loss of 10–15% of body weight with Ozempic (Semaglutide) and 15–20% with Mounjaro (Tirzepatide) over 6–12 months — when combined with dietary modification and lifestyle change. Individual results vary based on starting weight, dietary compliance, lifestyle modification, and individual metabolic response to medication.

The most common side effects are gastrointestinal — including nausea, vomiting, diarrhoea, and constipation — particularly during the initial weeks of treatment and following each dose increase. These typically subside as the body adjusts. Eating smaller portions, avoiding high-fat foods, and staying well hydrated significantly reduces side effect severity. Serious side effects are rare but include pancreatitis — contact your physician immediately if you experience severe abdominal pain.

Weight loss injection pricing at Vivari Aesthetics depends on the medication prescribed, dosage strength, and duration of your program. A personalised, transparent investment breakdown is provided following your comprehensive medical assessment and medication selection consultation. Both Ozempic and Mounjaro pricing is discussed in full during your initial appointment.

Yes — GLP-1 medications can be discontinued once your weight loss goal is achieved and your dietary and lifestyle habits are sufficiently established to maintain your results independently. Our comprehensive nutritional and lifestyle coaching program is specifically designed to embed the sustainable habits that preserve your weight loss results after medication cessation — making long-term maintenance genuinely achievable.

Vivari Aesthetics offers a level of medically supervised GLP-1 weight loss care that goes beyond simple prescription. By combining Ozempic or Mounjaro therapy with personalised nutritional guidance, lifestyle coaching, and continuous medical monitoring, we ensure results that are not only clinically meaningful during the program but behaviourally reinforced and enduringly sustainable beyond it.

Vivari Aesthetics is the premier destination for weight loss injections in Johannesburg, South Africa, combining medical precision with five-star care. Conveniently located near Lanseria International Airport, we welcome patients from across South Africa and internationally who seek medically supervised weight loss, metabolic transformation, and results that are both clinically significant and enduringly life-changing.

The Art of the Subtle Transformation

In medically supervised weight loss, excellence is measured not in the speed of results — but in their sustainability, their clinical significance, and their transformative impact on health, confidence, and quality of life. The Vivari Weight Loss Injection approach combines clinically proven GLP-1 therapy with comprehensive behavioural support to achieve a result that is both meaningfully transformative and genuinely enduring. Our commitment is to a weight loss journey that delivers real, lasting metabolic change — never a temporary fix, a superficial outcome, or an unsupported result.

A Note on Clinical Maturation: Weight loss outcomes with GLP-1 therapy vary between individuals based on starting weight, medication selection, dietary compliance, lifestyle modification, and individual metabolic response. Clinical trials report average weight loss of 10–15% of body weight with Ozempic and 15–20% with Mounjaro over 6–12 months. Patients who engage fully with every dimension of the Vivari program — including the nutritional guidance, lifestyle coaching, and long-term maintenance phase — consistently achieve the most significant and enduring metabolic transformations.

05 | THE ELITE CHOICE

The Celebrity Spotlight

THE ART OF MEDICALLY SUPPORTED WEIGHT LOSS

In Hollywood and global elite circles, the conversation around weight management has shifted profoundly. The world’s most celebrated public figures have openly embraced medically supervised approaches — moving away from unsustainable crash diets and extreme exercise regimes toward clinically proven, hormonally supported weight loss programs that deliver real, lasting results with dignity and expert care.

From Oprah Winfrey’s celebrated openness about her GLP-1 medication journey to Elon Musk’s widely reported use of Wegovy (Semaglutide) for weight management, the world’s most high-profile individuals have quietly normalised the use of medically supervised weight loss tools as a legitimate, intelligent approach to a genuinely complex health challenge. The “Vivari Journey” isn’t about a dramatic before-and-after moment — it’s about the compassionate medical expertise, comprehensive metabolic support, and clinically proven hormonal therapy that transforms not just the body, but the relationship with health, food, and confidence for a lifetime.

Why Specialist Weight Loss Injections are the Elite Standard:

💎 Clinically Proven & Medically Endorsed: Ozempic and Mounjaro are among the most rigorously studied weight management medications in medical history — with clinical trials demonstrating average weight loss of 10–20% of body weight, cardiovascular risk reduction, and significant metabolic health improvement in appropriate candidates.

👁️ Complete Discretion: Weekly self-injection at home — with no clinic visits between monthly reviews, no visible treatment evidence, and no recovery period — makes GLP-1 therapy the most discreet medically supervised weight loss intervention available, entirely on your own terms and timeline.

✦ Comprehensive Medical Support: Unlike online prescription services offering medication alone, the Vivari program surrounds every patient with personalised nutritional guidance, lifestyle coaching, and continuous medical monitoring — ensuring every dimension of your weight loss journey is expertly supported throughout.

◎ Lasting Metabolic Transformation: We don’t simply prescribe medication — we deliver a comprehensive, medically guided transformation program that combines GLP-1 therapy with deep nutritional and behavioural recalibration for weight loss results that endure long after the medication period ends.

06 | THE VIVARI INVESTMENT

A Legacy of Lasting Metabolic Health

The Specialist Weight Loss Injection program at Vivari is a comprehensive medical investment in lasting metabolic transformation — combining clinically proven Ozempic (Semaglutide) or Mounjaro (Tirzepatide) therapy with personalised nutritional guidance, lifestyle coaching, and continuous medical monitoring throughout the complete treatment period. For patients seeking a more structural weight loss intervention, our Intragastric Balloon or Endoscopic Sleeve Gastroplasty (ESG) programs offer non-injection alternatives within our comprehensive weight loss portfolio.

To ensure the highest standard of medical focus, we require a comprehensive pre-program health assessment. Your consultation fee will be credited toward your treatment program should you choose to proceed.

The Treatment Investment
Weight loss injection pricing at Vivari is determined by the medication prescribed, dosage strength, and program duration — all assessed during your initial medical consultation. A personalised, transparent investment breakdown is provided after your comprehensive metabolic assessment and medication selection appointment.

OVERNIGHT PACKAGES

Extend your recovery in the quiet luxury of the Vivari Hotel. Our bespoke post-operative packages include:

Curated Nutrition

Specialized menus from our restaurant designed for optimal healing.

Lymphatic Support

Gentle spa treatments to reduce swelling and accelerate recovery.

Seamless Care

24/7 access to clinical staff within a five-star hotel environment.

To ensure every patient receives the undivided attention and surgical expertise required for a bespoke transformation, we operate a refined pre-consultation process.

Your journey begins with a comprehensive clinical questionnaire. This initial diagnostic assessment allows our surgical team to review your unique facial and body architecture before your private appointment.

Initial Assessment Fee: R1,000

An additional R1,250 applies for an in-person consultation.
Should you proceed with surgery, a total of R2,250
will be credited toward your procedure.

BEGIN NOW

Consultations are held in absolute confidence.
There is no obligation to proceed.